Oct 22, 2019 The early Mac team members in 1979 consisted of Jef Raskin, Brian Howard, Marc LeBrun, Burrell Smith, Joanna Hoffman, and Bud Tribble. Others began working on the Mac at later dates. Seventy-four days after the introduction of the 'Macintosh,' the company was only able to sell 50,000 units. Purpose: Post-operative breast cancer patients receive physiotherapy to improve range of motion, reduce pain, and increase strength. The aim of this study was to provide qualitative information about which techniques are utilised by physiotherapists in the management of post-operative breast cancer patients in a hospital physiotherapy outpatient department setting in Western Sydney, Australia.
- One cannot downgrade a new Mac to a older version of the OS X operating system to work with hardware/software like one can do with a Windows PC and certain 'Pro' versions or better. Apple is Evil, pure and simple. The head of Apple Product Security is a top NSA guy named David Rice.
- The Cell and Molecular Biology (CMB) program at Michigan State is an interdepartmental Ph.D. All members share a common interest in the mechanisms that regulate cell structure and function.
Home > HCAS > HCAS_PUBS > HCAS_JOURNALS > TQR Home > TQR > Vol. 24 > No. 1 (2019)
Article Title
Authors
Abstract
The recent literature shows an increase of breast cancer in women under 50, however still few are the studies which analyse the impact of the disease in this specific target age. This study aims at exploring the most prevalent topics in Italian cancer blogs of women who have received a breast cancer diagnosis before the age of 50, in order to understand their experience of illness and the characteristics of women's narrations at different times after diagnosis (1 year, 2 years, 3 years). We collected the textual corpus of 4 Italian breast cancer blogs and performed a thematic analysis. Five themes resulted, which, after interpretation using factorial mapping, fall into 3 sense vectors: toward the thought of the experience; from the external to the internal world; breast cancer: from rigidity to mobility. The blog analysis allows to build a first step of the scientific knowledge about the traumatic specificity of this experience, showing a need for processing the emotions. This allows to think about clinical support practices tailored to this group, in order to develop a diachronic processing of the experience and the construction of a new continuity of life.
Keywords
Breast Cancer, Younger Women, Cancer Blog, Narrative, Trauma Experience
Author Bio(s)
Maria Luisa Martino, PhD, is Principal Investigator of IMPRONTE Project - Breast Cancer Women: Innovative Model for Processing Traumatic Experience - at the Department of Humanistic Studies, University of Naples Federico II, Italy. Her research field is Clinical Health Psychology. She focuses on the life-threatening illness as potential traumatic experience. She deals with psychological research-intervention in hospital institutions with particular regard to the use and evaluation of different narrative devices as tools to promote wellbeing. Adopting quali-quantitative methods, she deepens models of processing the traumatic experience of illness based on the construction of meaning-making processes. Please direct correspondence to marialuisa.martino@unina.it.
Oct 22, 2019 The early Mac team members in 1979 consisted of Jef Raskin, Brian Howard, Marc LeBrun, Burrell Smith, Joanna Hoffman, and Bud Tribble. Others began working on the Mac at later dates. Seventy-four days after the introduction of the 'Macintosh,' the company was only able to sell 50,000 units. Purpose: Post-operative breast cancer patients receive physiotherapy to improve range of motion, reduce pain, and increase strength. The aim of this study was to provide qualitative information about which techniques are utilised by physiotherapists in the management of post-operative breast cancer patients in a hospital physiotherapy outpatient department setting in Western Sydney, Australia.
- One cannot downgrade a new Mac to a older version of the OS X operating system to work with hardware/software like one can do with a Windows PC and certain 'Pro' versions or better. Apple is Evil, pure and simple. The head of Apple Product Security is a top NSA guy named David Rice.
- The Cell and Molecular Biology (CMB) program at Michigan State is an interdepartmental Ph.D. All members share a common interest in the mechanisms that regulate cell structure and function.
Home > HCAS > HCAS_PUBS > HCAS_JOURNALS > TQR Home > TQR > Vol. 24 > No. 1 (2019)
Article Title
Authors
Abstract
The recent literature shows an increase of breast cancer in women under 50, however still few are the studies which analyse the impact of the disease in this specific target age. This study aims at exploring the most prevalent topics in Italian cancer blogs of women who have received a breast cancer diagnosis before the age of 50, in order to understand their experience of illness and the characteristics of women's narrations at different times after diagnosis (1 year, 2 years, 3 years). We collected the textual corpus of 4 Italian breast cancer blogs and performed a thematic analysis. Five themes resulted, which, after interpretation using factorial mapping, fall into 3 sense vectors: toward the thought of the experience; from the external to the internal world; breast cancer: from rigidity to mobility. The blog analysis allows to build a first step of the scientific knowledge about the traumatic specificity of this experience, showing a need for processing the emotions. This allows to think about clinical support practices tailored to this group, in order to develop a diachronic processing of the experience and the construction of a new continuity of life.
Keywords
Breast Cancer, Younger Women, Cancer Blog, Narrative, Trauma Experience
Author Bio(s)
Maria Luisa Martino, PhD, is Principal Investigator of IMPRONTE Project - Breast Cancer Women: Innovative Model for Processing Traumatic Experience - at the Department of Humanistic Studies, University of Naples Federico II, Italy. Her research field is Clinical Health Psychology. She focuses on the life-threatening illness as potential traumatic experience. She deals with psychological research-intervention in hospital institutions with particular regard to the use and evaluation of different narrative devices as tools to promote wellbeing. Adopting quali-quantitative methods, she deepens models of processing the traumatic experience of illness based on the construction of meaning-making processes. Please direct correspondence to marialuisa.martino@unina.it.
Anna Gargiulo, PhD in Gender Studies, is Post-doctoral Research Fellow at Department of Humanistic Studies, University of Naples Federico II, Italy. Visiting Researcher at Centre of Cultural Psychology of Aalborg University Denmark. Visiting Ph.D. Student at Medical University of Vienna. Psychology, Psychotherapist in training at IIPG (Italian Institute of Psychoanalysis Group). Adopting quali-quantitative methods, she studies the women's psychological health, deepening the experience of breast cancer and self-harming behaviors, also within virtual communities. Please direct correspondence to anna.gargiulo2@unina.it.
Daniela Lemmo, Psychologist, PhD in Gender Studies, is Post-doctoral Research Fellow at Department of Humanistic Studies, University of Naples Federico II, Italy. Her research activity field is Clinical and Health Psychology with a particular focus on women's experiences and narratives about oncological prevention and breast cancer. Her studies are dedicated to women's health in a gender perspective. She works with narrative devices as tools to promote well-being and adaptation to illness experience. Also, her scientific production, adopting a quali-quantivative methods, regards the themes of genetic mutation, oncological screening and breast cancer at a young age. Please direct correspondence to daniela.lemmo@unina.it.
Giorgia Margherita is Researcher in Psychodynamic Psychology at Department of Humanistic Studies, University of Naples Federico II, Italy. She teaches Dynamic Psychology on the Masters Degree in Clinical Psychology. Psychoanalytic-oriented Psychotherapist, member of IIPG (Italian Institute of Psychoanalysis Group) and of EFPP (European Federation for Psychoanalytic Psychotherapy in the Public Sector). Her research activity is related to the psychodynamic of groups, the psychopathology in online environments, narrative methods. She has also written books and articles on these topics, published in national and international journals. Please direct correspondence to margheri@unina.it.
Acknowledgements
Funding: This research was carried out in the frame of Programme STAR, financially supported by UniNA and Compagnia di San Paolo.
Publication Date
1-27-2019
Creative Commons License
Dancemazing mac os. This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 International License.
DOI
10.46743/2160-3715/2019.3646
Recommended APA Citation
Martino, M., Gargiulo, A., Lemmo, D., & Margherita, G. (2019). Cancer Blog Narratives: The Experience of Under-Fifty Women with Breast Cancer during Different Times after Diagnosis. The Qualitative Report, 24(1), 158-173. https://doi.org/10.46743/2160-3715/2019.3646
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The Gallo laboratory is interested in the understanding and therapeutic targeting of signaling pathways that govern cancer progression. In particular, we have focused on the mixed-lineage kinase (MLK) family (Figure 1) and their roles in cancer invasion and metastasis, particularly in the context of breast cancer. We have demonstrated a critical role for MLK3 in triple-negative breast cancer metastasis (Figure 2), in regulating both focal adhesion turnover during cell migration and gene expression during invasion and metastasis. In addition we are studying the roles of MLK family members and related signaling in lung cancer, glioblastoma, and melanoma.
Triple-negative breast cancers (TNBCs) have high rates of metastasis and early metastatic recurrence and lack targeted therapies. During cancer metastasis, individual or small groups of tumor cells must break away from the primary tumor, invade through extracellular matrix, intravasate through the endothelial layer of the vasculature to enter the bloodstream. Subpopulations of these 'circulating tumor cells' are responsible for metastatic colonization. We are studying the molecular characteristics of circulating tumor cells derived from a TNBC model, including their gene expression and signaling pathways, with the aim of identifying important druggable targets to combat breast cancer metastasis.
Vinnie Cancer Mac Os 11
Estrogen receptor-positive (ER+) breast tumors are typically less aggressive than TNBCs and often respond to endocrine therapies, but endocrine resistance and late metastatic recurrence are major causes of mortality in these women. Late metastatic recurrence is thought to occur upon reacativation of dormant tumor cells that have disseminated to distant organs. We are investigating pathways responsible for reactivation of dormant tumor cells, in order to identify appropriate drug targets.
Figure 2. MLK3 signaling in triple-negative breast cancer.
Our laboratory uses diverse approaches and techniques to study mechanisms of tumor proliferation, invasion and metastatic outgrowth including 3D organotypic assays, cell biology, animal models, mass spectrometry, and biochemical techniques.
We collaborate with the Conrad lab (Microbiology & Molecular Genetics) in identifying mechanisms and alternative therapeutic strategies for endocrine resistant breast cancer. In collaboration with the Neubig lab in Pharmacology & Toxicology, we are exploring appropriate combination therapies in drug-resistant melanoma.
